Future Perspectives in Small-Diameter Vascular Graft Engineering

Membrane Engineering: Future Perspectives

Tissue engineering of small diameter vascular grafts.

Tissue engineering, using either polymer or biological based scaffolds, represents the newest approach to overcoming limitations of small diameter prosthetic vascular grafts. Their disadvantages include thromboembolism and thrombosis, anticoagulant related haemorrhage, compliance mismatch, neointimal hyperplasia, as well as aneurysm formation. This current review represents an overview about pr...

membrane engineering: future perspectives

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Electrospun Bilayered Vascular Scaffolds for Engineering Small Diameter Blood Vessels

336 ©2013 Society For Biomaterials

Polymer scaffolds for small-diameter vascular tissue engineering.

To better engineer small-diameter blood vessels, a few types of novel scaffolds were fabricated from biodegradable poly(L-lactic acid) (PLLA) by means of thermally induced phase separation (TIPS) techniques. By utilizing the differences in thermal conductivities of the mold materials, the scaffolds with oriented gradient microtubular structures in axial or radial direction were created using be...